hair loss
Lilly invests in AI-designed hair growth drug
Eli Lilly is investing $40 million in Absci, a small AI drug developer, as part of a $100 million financing centered on an experimental hair loss treatment. The drug, ABS-201, targets the prolactin receptor and is being tested in a Phase 1 study for androgenetic alopecia. The company plans to study it in endometriosis as well.
The investment underscores growing pharma interest in aesthetic medicine, STAT’s Allison DeAngelis writes. Lilly, flush with cash from the GLP-1 boom, has been on a spending spree of late — investing nearly $30 billion on deals in the past couple years. Lilly won’t work on developing ABS-201; Absci wants to keep that in-house.
“We're wanting to have our own sovereignty, [while] being able to be mentored by a leading pharma that is going in this direction,” CEO Sean McClain told STAT. “So for us it's an exciting win-win.”
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infectious disease
Trial set to test Bundibugyo Ebola treatments
A clinical trial is set to begin next week to test how best to treat the burgeoning Bundibugyo ebolavirus outbreak in the Democratic Republic of the Congo. It’ll study the efficacy of Gilead’s remdesivir, MappBio’s monoclonal antibody MBP-134, and a combination of the two to treat the virulent disease, STAT’s Helen Branswell writes.
The outbreak has surpassed 1,000 confirmed cases and caused more than 275 deaths in the Congo, with additional cases reported in Uganda. Because no vaccine or therapy has been proven effective against the Bundibugyo species — a rarer form of Ebola first identified in 2007 — researchers hope the study will provide critical evidence on potential treatments. The trial, backed by the WHO and a consortium of international partners, is expected to enroll roughly 1,000 participants.
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